Would you mind handing me a piece of that possum there at your feet?

As Slither begins, we are introduced to one of the few leaders of Wheelsy's pack - successful, albeit oafish, local businessman Grant Grant (MICHAEL ROOKER, Henry: Portrait of a Serial Killer). With beautiful young wife Starla (ELIZABETH BANKS, The 40-Year-Old Virgin), a large house and fat bank account, Grant truly relishes his "big fish-small pond" role in the town. Other than the fact that the passionate love he feels for his woman goes completely unrequited, he's a man content. But things are about to change for Grant in ways no one could have ever imagined.

When Killer Slugs Attack: Getting Scared on Set

On a humdrum evening, Grant hits the local honky-tonk for an all-night bender. There he encounters Brenda Gutierrez (BRENDA JAMES), the younger sister of an old girlfriend, who's more than willing to listen to Grant's woes. Abandoning their drinks for a moonlight stroll, the pair discovers something slimy in the woods behind the bar. Near the remains of what appears to be a meteor, Grant and Brenda find a trail of glistening, noxious ooze and a pulsating, unidentifiable mass. Suddenly, the glob comes to life and overtakes Grant, penetrating his body with a pustule-covered tentacle. An alien parasite has found and infected its unlucky human host, an unwilling transporter who now must continue to infect others in order to survive.

Signs of Grant's transformation are instantly apparent: the extended periods of time he spends in his basement amassing meat products; the strange sounds and odors Starla notices emanating from the bowels of their home; his erratic behavior towards his wife - sometimes loving and tender, then suddenly ferocious and aggressive. And most gruesomely, the denizens begin to suspect Grant's involvement in an unusual number of missing pets and farm animals around town.

With each day that passes, Grant becomes less and less human, evolving into a bloodthirsty creature driven by a primal need to kill and destroy the uninfected. Unfortunately, Grant's not the only problem. He has begun spawning scores of giant slugs that are out to inoculate any redneck into whom they can get their siphons.

Now joining Starla on her quest to stop Grant and the infected is her former high school beau, local chief of police Bill Pardy (NATHAN FILLION, Serenity). A handsome everyman with a burning love for Starla, Pardy gets suspicious of his old rival and leads the charge to take him down. The pair gathers a makeshift crew of uninfected, including foul-mouthed Mayor Jack MacReady (GREGG HENRY, Star Trek: Insurrection) and smart-ass teen beauty Kylie Strutemyer (TANIA SAULNIER) to help stop the evil plague laying siege to Wheelsy

As the rebels attempt to avoid both the slippery slugs that just want to worm inside of them and their former neighbors-turned-meat-eating zombies, it's anyone's guess as to who will stay slug-free. But when the ragtag team comes face-to-face with an ancient, vengeful entity beyond all human comprehension, fierce alliances will be forged, former friends will be destroyed and a hilariously gruesome showdown will take place - hillbilly style.

Scream out! 10 Aug '06